WebThiourea and some monosubstituted thioureas are toxic and tumorogenic while 1,3 … WebApr 4, 2024 · Thioureas are the commonly used antithyroid drugs in the clinical setting, such as methylthiouracil, propylthiouracil, thiamzole, and carbimazole, which highlights the druggability of thiourea derivatives as antibacterial agents. Thus, we evaluate the cytotoxicity and drug likeness of compound TD4.
Design, synthesis, characterization, and biological evaluation of ...
WebMar 10, 2002 · Some compounds having thionamide structure inhibit thyroid functions. Such antithyroid thionamides include mercaptomethylimidazole (methimazole), thiourea and propylthiouracil, of which mercaptomethylimidazole is widely used to treat hyperthyroidism. Undesirable side effects develop from these drugs due to extrathyroidal actions. Webthiourea: ( thī'ō-yū-rē'ă ), An antithyroid compound of the thioamide group, with the same … black cherry kombucha
Synthesis and anticancer activity of thiourea derivatives ... - PubMed
WebApr 10, 2024 · Thiourea derivatives, containing both sulfur and nitrogen, have gained significant attention in drug development research in recent years . These compounds have demonstrated useful properties and have shown potential as active ingredients in antibacterial, antituberculosis, and anticonvulsant drugs. WebThiourea drugs (methimazole & propylthiouracil (PTU)) Side Effects: maculopapular pruritic rash, edema, arthralgia, fever, severe agranulocytosis (reversible), hepatitis, lupus-like syndrome, goiter formation with prolonged treatment. Use with caution in ____ lysosomal proteases Iodide salts (potassium iodide)-oldest remedy -seemingly paradoxical: WebThiourea was the drug initially used to treat Graves’ disease; however, it had considerable … black cherry kool-aid