WebAlthough lithium has been used for over 50 years in treatment of bipolar disorder, the mechanism of action is still unknown. Lithium's therapeutic action may be due to a number of effects, ranging from inhibition of enzymes such as glycogen synthase kinase 3, inositol phosphatases, or modulation of glutamate receptors. WebThis paper summarizes the knowledge base on side effects and toxicity and suggests optimal management of these problems. Thirst and excessive urination, nausea and …

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WebNeurological side effects of lithium At therapeutic levels, lithium can cause a persistent fine hand tremor, muscle weakness and rarely, extrapyramidal features. Tremors may be treated with a beta-blocker. Patients with lithium toxicity may have impaired consciousness, apathy, hyperreflexia, hypertonia, seizures and rarely, death. Web23 jan. 2012 · The most effective long-term treatment for bipolar disorder is lithium. It offers protection against depression and mania and reduces the risk of suicide and short-term mortality. flow away from the shore

Lithium side effects: Long term and short term - Medical …

WebAnalysis of these four studies showed that lithium had a negative effect on memory and speed of information processing, often without subjective complaints or awareness of … WebLithium is taken orally. [2] Common side effects include increased urination, shakiness of the hands, and increased thirst. [2] Serious side effects include hypothyroidism, diabetes insipidus, and lithium toxicity. … Web17 dec. 2016 · Gastrointestinal side effects—typically nausea and/or diarrhea—are relatively common side effects from lithium and have been recognized since the earliest lithium studies. Nausea, seen in 10–20% of lithium-treated patients, tends to be more prominent early in treatment and is much less common in long-term therapy (Schou et al. … flow away from stress